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MEDICAL ONCOLOGY

Overview

With the rising number of cancer patients and with the need for comprehensive cancer care facility, the Department of Medical Oncology, at Amala Institute of Medical Sciences, offers a wide range of cancer treatment options, having a well-equipped team of highly qualified Medical Oncologists and Haemato-oncologists experienced in diagnosis, treatment planning, Chemotherapy procedures, targeted therapy, Bone marrow Transplantation and Hormonal Therapy to all patients of all age groups with solid organ tumors and Haematological malignancies.The department also owns a well-equipped Bone marrow transplant unit, which started rendering services from Dec 2021, and aims at delivering utmost cost-effective care to the transplant patients, with inclusion of the best possible infrastructure and facilities.The Medical Oncology department also has a well-functioning Clinical Research Unit (CRU), which hosts three different types of Govt. funded projects (NOCI-BIRAC, HCC & ICMR-HBCR), mainly focusing on cancer registry and conducting clinical trials.

Facilities

  • Systemic therapy of all cancers
    •  Chemotherapy
    • Immunotherapy
    •  Targeted therapy
  • Paediatric oncology
  • Paediatric and adult leukemia unit

  • Precision oncology
  • Day care therapy unit and Procedure room
  • Bone marrow transplantation Unit Autologous
  • Allogenic

    Related 

    Maternal unrelated

     Haploidentical donor transplantion

  • Neutropenia ICU with Semi ICU facility
  • Clinical research unit
  • Molecular oncology lab
  • Comprehensive cancer registry

Services

 services available on all working days from 8:00AM to 4:00PM

Special evening OPD facility available on specific days in a week from (5:00PM TO 7:00PM)

Various speciality clinic services including breast clinic , Head and neck clinic, Genitourinary, Gynaec oncology clinic, GIT clinic, chest clinic and other clinical services available with the aim of delivering the best possible updated treatment.

 Various OPD procedures such as bone marrow aspiration and biopsy, blood and blood product transfusions, central line care, dressings etc are being carried out in a well facilitated set up by well trained doctors and nursing staff.

Different chemotherapy protocols are being delivered on a day care basis for which department owns a ( 17 bedded) day care chemotherapy room with well trained staffs functioning from morning 9:00Am to 4:00pm on all working days.

Department of Medical Oncology is also equipped with an ICU which functions exclusively with well trained ICU nursing and supportive staff. for handling neutropenia and other oncological emergencies.

Department is updated with Bone marrow transplantation unit which handles both autologous and allogenic transplants , aiming at delivering utmost cost effective and high quality care to all the transplant patients.

 The department also has a well-functioning Clinical Research Unit (CRU) which hosts different types of projects (NOCI-BIRAC, HCC &

ICMR-HBCR). CRU also handles hospital based cancer registry and clinical trials , which offer a great opportunity for cancer patients in getting the latest treatment.

 The department of Medical oncology is the first in private sector, under the Kerala University of Health Sciences to get approval for an annual intake of DM seats per year. The department provides one of the best evidence based training in the subject with various other academic activities like clinical discussion, journal clubs, presentations and discussions.

 As this institute is a comprehensive cancer centre, alll the complicated oncology cases are discussed in detail for planning the best treatment in a multidisciplinary board consisting of medical oncologists, surgical oncologists, radiation oncologists, pathologists, radiologist

CAR T-Cell (Chimeric Antigen Receptor T-Cell) therapy is one of the most groundbreaking innovations in modern cancer treatment. This advanced form of immunotherapy modifies a patient’s own T-cells (critical immune cells) to identify and destroy cancer cells with remarkable precision. Unlike conventional treatments like chemotherapy or radiation that attack cancer directly, CAR T-Cell therapy empowers the body’s immune system to fight cancer at a cellular level. Designed primarily for haematologic malignancies such as Acute Lymphoblastic Leukaemia (ALL) and certain types of lymphomas, CAR T-Cell therapy has transformed outcomes for patients who previously had limited treatment options. The success story of Emily Whitehead—the first paediatric patient in the world to successfully undergo CAR T-Cell therapy at Children’s Hospital of Philadelphia (CHOP)—remains a global testament to its life-saving potential. Diagnosed with relapsed ALL, Emily was treated with an experimental CAR T protocol after conventional therapies failed. Thirteen years later,today she remains cancer-free, offering hope to thousands. Since then, over 35,000 patients worldwide have benefitted from this pioneering therapy. CAR T cell therapy involves collecting a patient’s T-cells, genetically engineering them in specialised labs to express synthetic receptors that recognise cancer cells, expanding them in large numbers, and re-infusing them into the patient. While it is a highly personalised and complex procedure, the therapy has shown cure rates of up to 60% in otherwise treatment-resistant leukaemia and lymphoma cases. Though side effects such as Cytokine Release Syndrome (CRS) and neurotoxicity require expert management, advances in clinical care have made these risks increasingly controllable. Amala Institute of Medical Sciences is proud to be at the forefront of cellular therapies in India. As the first centre in the country to introduce Tumour-Infiltrating Lymphocyte (TIL) Therapy (Another form of cell therapy) and the second in Kerala to offer CAR T-Cell therapy, Amala continues to set new standards in precision oncology. With state-of-the-art infrastructure, dedicated expertise, and a mission to offer cutting-edge care, Amala remains a trusted destination for advanced cancer therapies in India.


Faculties

Dr Anilkumar Thazhatha Jose
Reg.No: TCMC 17508
Professor & HOD
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Dr Ashwin Oommen Philips
Reg.No: KSMC 39765
Professor
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Dr. Unnikrishnan P
Reg.No: TCMC 44642
Associate Professor
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Dr. Advait M K
Reg.No: TCMC No:43850
Assistant Professor
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CME

CME Details Date of Conduct
Name : Medical Research Seminars
Theme/Subject : An Overview and common pitfalls
Credit Hours : 1

2024
Name : De-Code R: Mastering the essentials
Theme/Subject : Learn the fundamentals of research, master data manipulation technique, statistical analysis
Credit Hours : 8.30am-5.00pm

2024
Name : Research Grant Writing Workshop
Theme/Subject : An Empowering workshop on Research Grant Writing , Learn essentials skills,Gain insights from experts

2024
Name : Amala Hemato-Oncology Conference 2023
Theme/Subject : 1. Stem Cell transplantation in developing countries 2. Lymphoma 3. Multiple Myeloma 4. Neutropenic Care 5. BMT Unit from nursing perspectives
Credit Hours : 1.5

2023
Name : Molecular method and precision Oncology -an introducing course -7
Theme/Subject : Cell biopsy

2022
Name : Amala Cancer Registry Annual meeting
Theme/Subject : Cancer Registry

2021
Name : Crossroads-2021
Theme/Subject : Career guidance workshop

2021
Name : ABCC-2020
Theme/Subject : CARCINOMA BREAST

2020
Name : ABCC-2020
Theme/Subject : CARCINOMA BREAST

2020

Publications

  • Unnikrishnan P, Nair SG, Sugeeth MT, Benson R, Mony RP. Cutaneous Metastasis from Sacral Chordoma: A Case Report. IJBC 2019; 11(3): 109-110.
  • Puthillathu Unnikrishnan, Geetha Narayanan, Bhavya S. Kumar, and Nandini Devi. B-lymphoblastic lymphoma of the rectum. Proc(Bayl Univ Med Cent) 2017; 30(3): 336–337
  • Geetha Narayanan, Unnikrishnan P, Bhavya S. Kumar. Hypercalcemia and osteolytic lesion as presenting feature in an adult ph positive acute lymphoblastic leukemia patient mimicking multiple myeloma. ejpmr, 2017,4(03), 490-491.
  • Joseph R, Anoop TM, Unnikrishnan P. Carcinoma breast with ectopic intrathoracic thyroid tissue: A rare presentation. Indian J Med Paediatr Oncol 2020;41:758-60
  • Rakul Nambiar K, Rona Joseph P, Unnikrishnan P, Geetha N. Non Hodgkin’s lymphoma of the scalp - A case report. Sch J Med Case Rep 2016; 4(6):376-378
  • Sugeeth MT, Vishnu H, Unnikrishnan P. Geetha N. Non-Hodgkin’s Lymphoma of the Hard Palate - A Case Report. Sch J Med Case Rep 2016; 4(7):469-470
  • Danish E, Vishnu H, Unnikrishnan P, Sharath K Krishnan, T.M. Anoop. A case of fibro muscular dysplasia with abdominal aortic aneurysm. Sch J Med Case Rep 2016; 4(6):376-378.
  • Anoop T. M, Bhavya S Kumar, Gayatri Gopan, Unnikrishnan P. Retroperitoneal Evans Tumour. Sch J Med Case Rep 2017; 5(1):22-23
  • Anoop TM, Joseph R, Unnikrishnan P, Thomas F, Venugopal M. Taxane induced acute interstitial pneumonitis in patients with breast cancer and outcome of taxane rechallenge. Lung India 202
  • Ashwin P, Venkatraman et al- Efficacy of Single Dose Rasburicase (1.5 mg) for Prophylaxis and Management of Laboratory Tumor Lysis Syndrome, Indian Journal of Hematology and Blood Transfusion 34(1) · March 2018
  • Ashwin P, Venkatraman et al -Experience with pemetrexed maintenance with NSCLC from tertiary level hospital.Dr MGR University e-journal.
  • Eqbal A, Goodliffe L, Masoom H, Ashwin P et al. The Syncopal Sarcoma. J Am Coll Cardiol Case Rep. 2022 Aug, 4 (16) 1037–1041
  • Mall A, Negi P, Philip AO, Kingsley PA. Induction chemotherapy in head and neck cancers – Boon or bane? J Can Res Ther 2023;19:420-5.
  • Philips A, Soumya P, Sunu C, Moharana, et al Real-World Experiences of Next-Generation Sequencing in Oncology: From an Indian Multicenter Registry andCollaborative Centers. Indian Journal of Medical and Paediatric Oncology. 10.1055/s-0044-1779275.
  • A Case of Choroid Plexus Carcinoma with Lung Metastasis-Dr Advait.M. K, Dr.D. Bhargavi, Dr Ravi Teja.C, Dr P Sindhu, Dr V Aditya, DrV VRamesh Chandra, Dr.B.Sreenivasa Rao, Dr A. Sreelekha-IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 22, Issue 1 Ser.6 (January. 2023), PP 57-60
  • A Case of Synchronous Primary of CA Breast and Non-Hodgkins Lymphoma Dr. Advait. M K., Dr. D. Bhargavi, Dr. Ravi Teja C., Dr. P. Sindhu, Dr. V. Aditya, Dr. B. Sreenivasa Rao, Dr. A. Sreelekha, Dr. S. Nagesh Kumar-Scholars Journal of Medical Case Reports Abbreviated Key Title: Sch J Med Case Rep ISSN 2347-9507 (Print) | ISSN 2347-6559 (Online)
  • Response Of Neoadjuvant Chemotherapy Based on Different Subtypes of Breast Cancer Dr Advait.M.K, Dr D. Bhargavi, Dr Ravi Teja.C, Dr P.Sindhu, Dr B.Manilal,Dr.V.Aditya IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 22, Issue 7 Ser.8 (July. 2023), PP 29-31
  • Comparative Evaluation of Radiotherapy with Concurrent Weekly Cisplatin versus Concurrent Daily Erlotinib and Weekly Cisplatin in Locally Advanced Carcinoma Cervix Shyamji Rawat, M K Advait, Pranjil Mandloi-- International Journal of Scientific Study | January 2018 | Vol 5 | Issue 10,48-54
  • The Comparative Evaluation of Radiotherapy with Concurrent Weekly Cisplatin and Irinotecan versus Concurrent Weekly Cisplatin in Locally Advanced Carcinoma Esophagus-- Dr. Laxmi Singotia,Dr. Piyush Jain, Dr. Rajesh Kumar Jain,Dr. Advait.M. K-- IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 15, Issue 4 Ver. XI (Apr. 2016), PP 70-72
  • Krishna SR, Muzumder S, Johnson S, Srikantia N, U AH, Ghosh S, Majumder R. Predictive Factors for Esophageal Stricture Following Definitive Chemoradiotherapy in Esophageal Carcinoma. J Gastrointest Cancer. 2025 Feb 14;56(1):65. doi: 10.1007/s12029-025-01192-1. PMID: 39953181.